Robert De Niro and his wife, Grace Hightower, have reportedly been canceled after more than 20 years of marriage, according to multiple sources.
A source close to the former couple told Page Six on Tuesday that De Niro, 75, and Hightower, 63, "are not living together at this time."
"Sometimes things do not work the way you expect or want them to," said another informant to People magazine.
A representative of De Niro did not respond immediately to the request for comments from Fox News.
After dating for almost 10 years, the star of "The Wizard of Lies" and Hightower got married in 1997. Then they welcomed two children together: their son Elliott, 20, and their daughter Helen, 6 .
This is not the first time that the couple has separated. For People, two years after their wedding, De Niro filed for divorce and there was reportedly a dispute over the custody of his son. However, things were softened and the divorce was not finalized.
De Niro was married to Diahnne Abbott, with whom he shares two children: his daughter Drena, 47, and his son Raphael, 42 years old. She also has twin sons of 23 years, Julian and Aaron, with the former Toukie Smith.